Dr. Wira is board certified in Internal and Emergency Medicine with specialization in Stroke and Emergency Critical Care. He provides clinical care in the Yale Department of Emergency Medicine (DEM) and also for the Division of Vascular Neurology in the Department of Neurology. He has performed research in the areas of stroke, sepsis, and cardiac arrest. Dr. Wira performed laboratory based cardiac arrest hypothermia studies in animal models that changed the 2010 AHA guidelines, he was a post-hoc member of the Early Goal Directed Collaborative Group which performed a landmark clinical trial at Henry Ford Hospital in Detroit, MI on septic shock patients, and is involved in multiple ischemic stroke clinical trials. With Drs D’Onofrio and Sheth, Dr. Wira brought SIREN to Yale .  He has been a volunteer for the AHA/ASA, serving as Chair of various scientific subcommittees, and as a member of the Stroke Council Leadership Committee.