ICECAP

ICECAP

Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

NCT04217551

|

UH3HL145269


Status: Enrolling

Trial Updates


Overview


Neurological death and disability are common outcomes in survivors of cardiac arrest. Therapeutic cooling of comatose patients resuscitated from shockable rhythms markedly increases the rate of good neurological outcome, but poor outcomes still occur in as many as 50%, and the benefit of cooling in those resuscitated from asystole and pulseless electrical activity has not been shown in a randomized study.

The Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP) study will enroll comatose adult survivors of out of hospital cardiac arrest that have already been rapidly cooled using a definitive temperature control method. Those with and without initial shockable rhythms will be studied as distinct populations (maximum of 1800 subjects over four years). ICECAP will determine if identifying an optimal duration of cooling can improve outcomes, and if development of a duration response curve can substantiate efficacy in a wider patient population.

Contact


Emergency 24-Hour Study Hotline:

1-833-4-ICECAP (1-833-442-3227)

Outcomes Team:

Angi Caveney (angif@umich.edu), Lead Neuropsychologist;
Joy Black (joypink@umich.edu), Central Outcomes Assessor;
Courtney Miller (coraymon@umich.edu), iPad & iCloud support ;
& Sofia Perez (persof@umich.edu), Co-trainer & QA Reviewer

Education (training, website access, material development, technical support):

Courtney Miller (coraymon@umich.edu)

WebDCU Support (user account requests, technical support, CRF completion):

Sara Butler (butlers@musc.edu) (843) 792-1599 & Sarah Wells (wellssar@musc.edu) (843) 876-1129

Site Management and Other Inquiries:

Nia Bozeman (nbozeman@umich.edu)
or ICECAP-contact@umich.edu

Finances:

Valerie Stevenson (vwillis@umich.edu

For a comprehensive list of contacts:

SIREN Contact Page